Cosmetic efficacy claim studies

Home Cosmetic efficacy claim studies

AssayMethod detailsTimeline
Cytotoxicity MTT and CTG, in keratinocytes (HaCat), normal dermal fibroblast and melanoma cells (murine B16/F10) separately or co-culture2-3 weeks
Anti aging effects (Skin regeneration and anti-wrinkle) Upregulation of Collagen-I synthesis and downregulation of hyaluronidase, elastase, collagenase-14 and MMP-11
Melanin formationMelanin inhibitory activity in B16/F10 murine melanoma cells
Cell migration and healing effects Microscopy
Phototoxicity In Vitro 3T3 NRU Phototoxicity Test
Skin whitening Tyrosinase inhibitory assay (cell-free)
In-vitro skin irritation and corrosion test Reconstructed Human Epidermis (RHE) (According to OECD guidelines)5-6 weeks

• Custom in-vitro assay development
• Human volunteer studies
• Animal studies

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